ANALYSIS OF FUROSEMIDE AND VABOMERE DRUGS 2
Analysis of Furosemide and Vabomere Drugs
Utilization of Furosemide in Treatment of Ascites in Cirrhotic Patients
Research depicts ascites as the most prevalent complication in patients suffering from
liver cirrhosis. Although preliminary management of this disorder with a low-sodium diet and
diuretic treatment has proven to be effective, a significant percentage of cirrhotic patients fail to
respond to these treatments (Emmett & Seldin, 1997). As a result, Furosemide is frequently
adopted in the treatment of ascites in cirrhotic patients. However, it is vital for physicians to note
that the drug is a potent diuretic which if administered in excessive amounts can instigate
diuresis and electrolyte depletion (Fuller & Ingalls, 1981). Owing to this side effect, the
medication should be administered under careful supervision, and the dose schedules should be
adjusted to meet the patients’ needs and preferences (Emmett & Seldin, 1997). Additionally,
administration of Furosemide in cirrhotic patients may cause an impulsive electrolyte and fluid
imbalance, which may lead to hepatic coma.
Utilization of Vabomere in Treatment of UTI and Pyelonephritis Disorder
Recently, the US Food and Drug Administration (FDA) approved the use of Vabomere
drugs for the treatment of adults with complicated Urinary Tract Infection (UTI) and
Pyelonephritis disorder that is caused by a specific bacteria (Brooks, 2017). The drug is
manufactured with components such as antibiotics, meropenem, and vaborbactams which
impede the resistance mechanisms that are adopted by the pathogenic microorganisms.
According to clinical trials conducted before the launching of the drug, the medication is
associated with symptoms such as diarrhea, headaches, and infusion site reaction (Brooks, 2017).
Vabomere should not be prescribed to patients with ailments such as anaphylaxis, a disorder that
causes austere allergic reactions to beta-lactam drugs (Brooks, 2017). Moreover, to inhibit
