Biological Basis of Schizophrenia

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Biological Basis of Schizophrenia
There has been no exact treatment for Schizophrenia. Its exact cause is also not
known, but some of the risk factors include birth trauma, genetics, seasonality, abnormalities
in brain structure, abnormal brain chemistry as well as environmental factors. Potential
strategies for prevention of the groups at risks of this condition include refraining from drugs,
avoiding abusive or traumatic situations, keeping social ties strong, learning to manage stress,
seeing a psychiatrist, proper nutrition and exercise. Pregnant mothers should also get good
mental and physical health medical care.
Traumatic experiences, sexual abuse as well as brain injury may raise the risk of
Schizophrenia. According to research, children below 16 years when exposed to trauma were
three times more likely of becoming psychotic. When the trauma is severe, children are fifty
times more likely of becoming psychotic. Therefore, traumatic experiences and abusive
relationships should be avoided to reduce the rate of becoming psychotic.
It has been long recognized that abuse of drugs especially in early teens is an
important risk factor for schizophrenia. Results have indicated that interventions for parents
and their children which improves rule setting and communication may play a crucial role in
reducing subsequent drug abuse rate and accompanying problem behavior. However, more
research is needed for conclusive evidence. Studying such program’s efficacy in these
populations is therefore urgent given the grave early drug use consequences in youths who
are at risk for schizophrenia.
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Good nutrition, as well as plenty of exercises, are vital in preventing schizophrenia.
Glutathione is one of the essential brain antioxidants playing a crucial role in myelination and
maturation of the white matter. Glutathione may be replenished through nutritional
supplement; N-acetylcysteine which is its precursor amino acid. Several studies have
demonstrated that NAC neuroinflammation, redox balance restoration, and receptor
functioning of NMDA positive effects have preventive potential especially in the early
Schizophrenia stages (Sommer). Fish oil which is rich in omega -3- fatty acids (PUFAs)
may help to prevent worsening of psychotic disorders. They may also prevent kids at risk
or psychotic disorders. PUFAs have mild anti-inflammatory effects and some antioxidative
capacity on the brain.
In conclusion, while there is no exact treatment of schizophrenia, good nutrition and
plenty of exercises, refraining from drugs, avoiding abusive or traumatic situations, keeping
social ties strong, learning to manage stress, seeing a psychiatrist may serve as preventive
methods to reduce the risk of schizophrenia.
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Works Cited
Iris E Sommer, Carrie E Bearden, Edwin van Dellen, Elemi J Breetvelt, Sasja N Duijff, Kim Maijer,
Therese van Amelsvoort, Lieuwe de Haan, Raquel E Gur, Celso Arango, Covadonga M Díaz-
Caneja, Christiaan H Vinkers & Jacob AS Vorstman. "Early interventions in risk groups for
schizophrenia: what are we waiting for?" A Nature Research Journal (2016).
<https://www.nature.com/articles/npjschz20163>.

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