DMD chronic hypoventilation

Duchene Muscular Dystrophy (DMD) and Chronic Hypoventilation 1
By Students Name
Course Details
Professor’s Name
Name of the Institution
Student’s Name
Duchene Muscular Dystrophy (DMD) and Chronic Hypoventilation 2
Duchene Muscular Dystrophy (DMD) and Chronic Hypoventilation
Explain how DMD results in hypoventilation.
The disease affects the breathing muscles making breathing a problem since the muscles
are weakened and the result is hypoventilation (Fiorentino, Pisano & Annunziata, 2016).
Define hypoventilation and explain what would happen to pulmonary ventilation
and alveolar ventilation rates as well arterial PO2 and PCO2 compared to a normal
individual (use values to support your answer).
Hypoventilation is a physiological state where there are reduced amounts of air entering
the lungs leading to reduced oxygen levels and increased carbon dioxide levels in the lungs. In
alveolar hypoventilation, the arterial PCO2 is 45 mm Hg and arterial PO2 56 mm Hg as opposed
to 35 mm Hg and 75mm Hg in normal persons respectively. In pulmonary ventilation the arterial
PCO2 is 40 mm Hg and arterial PO2 60 mm Hg as opposed to 35 mm Hg and 75mm Hg in
normal persons respectively. (Finkel, Goemans & Rummey, 2016).
If a healthy individual began to hypoventilate, what changes would you expect to
observe in their plasma pH and why?
Hypoventilation leads to increased levels weak carbonic acid in the blood which leads to
a reduction in the plasma pH and patient present with respiratory acidosis. (Hukins & Hillman,
Dayne, as is common with all individuals who suffer from chronic hypoventilation,
has a normal plasma pH. Why?
The normal plasma pH comes as a result of compensatory mechanism that ensures that
the respiratory acidosis is corrected. The body produces more bicarbonate ions to above 30
mEq/L neutralizing the acidity (Ogna et al., 2016).
Duchene Muscular Dystrophy (DMD) and Chronic Hypoventilation 3
Reference list
Hukins, C.A., and Hillman, D.R., 2000. Daytime predictors of sleep hypoventilation in
Duchenne muscular dystrophy. American journal of respiratory and critical care
medicine, 161(1), pp.166-170.
Burns, D.P., Arijit, R., McDonald, F., Wilson, R.J. and O’Halloran, K.D., 2016. Hypoventilation
in the Mdx Mouse Model of Duchenne Muscular Dystrophy. The FASEB
Journal, 30(1_supplement), pp.lb742-lb742.
Ogna, A., Salva, M.A.Q., Prigent, H., Mroue, G., Vaugier, I., Annane, D., Lofaso, F. and
Orlikowski, D., 2016. Nocturnal hypoventilation in neuromuscular disease: prevalence
according to different definitions issued from the literature. Sleep and Breathing, 20(2),
Fiorentino, G., Pisano, A. and Annunziata, A., 2016. Noninvasive Mechanical Ventilation in
Duchenne Muscular Dystrophy: What Have We Learned?. In Noninvasive Mechanical
Ventilation (pp. 333-338). Springer, Cham.

Place new order. It's free, fast and safe

550 words

Our customers say

Customer Avatar
Jeff Curtis
USA, Student

"I'm fully satisfied with the essay I've just received. When I read it, I felt like it was exactly what I wanted to say, but couldn’t find the necessary words. Thank you!"

Customer Avatar
Ian McGregor
UK, Student

"I don’t know what I would do without your assistance! With your help, I met my deadline just in time and the work was very professional. I will be back in several days with another assignment!"

Customer Avatar
Shannon Williams
Canada, Student

"It was the perfect experience! I enjoyed working with my writer, he delivered my work on time and followed all the guidelines about the referencing and contents."

  • 5-paragraph Essay
  • Admission Essay
  • Annotated Bibliography
  • Argumentative Essay
  • Article Review
  • Assignment
  • Biography
  • Book/Movie Review
  • Business Plan
  • Case Study
  • Cause and Effect Essay
  • Classification Essay
  • Comparison Essay
  • Coursework
  • Creative Writing
  • Critical Thinking/Review
  • Deductive Essay
  • Definition Essay
  • Essay (Any Type)
  • Exploratory Essay
  • Expository Essay
  • Informal Essay
  • Literature Essay
  • Multiple Choice Question
  • Narrative Essay
  • Personal Essay
  • Persuasive Essay
  • Powerpoint Presentation
  • Reflective Writing
  • Research Essay
  • Response Essay
  • Scholarship Essay
  • Term Paper
We use cookies to provide you with the best possible experience. By using this website you are accepting the use of cookies mentioned in our Privacy Policy.