Erythrocyte profile report

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Erythrocyte profile report
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Erythrocyte profile report
The erythrocytes also called the red blood cells are the cellular components of the blood,
many of which are in the blood circulation of the vertebrates. The erythrocyte gives the blood its
color, and they also carry the oxygen to the body tissues from the lungs. The mature erythrocyte
is biconcave, round and small in size and they appear to be dumbbell-shaped in their profile. The
erythrocyte is very flexible, and they assume the shape of a bell because it passes through tiny
vessels of the blood. They are covered with a cell membrane which is composed of proteins and
lipids, they lack a nucleus, but they contain hemoglobin which is a red iron-rich protein that is
responsible for binding oxygen
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Figure 1 The Red erythrocytes or red blood cells
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. Hoffman JF. Red blood cells, compasses and snap shots. Blood Cells, Molecules, and Diseases. 2018 Mar 21.
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. Erythropoiesis: Formation of Red Blood Cells. (2016, December 17). Retrieved from http://www.interactive-
biology.com/3969/erythropoiesis-formation-of-red-blood-cells/
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Figure 2 The Red erythrocytes or red blood cells
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The red blood cells develop in adult bone marrow or the fetal liver via a process called
erythropoiesis. This process is stimulated by the erythropoietin, cytokine hormone, which is
produced by the kidney following the detection of reduced oxygen level circulation. The main
function of the erythrocytes is binding the oxygen through hemoglobin and carrying it to the
tissues of the body. The erythrocytes are also able to induce vasodilatation by mediating nitric
oxide (NO) bioactivity effects in the diseases such as sepsis and pulmonary hypertension. In
particular, the erythrocytes discharge S-nitrosothiols when hemoglobin particles are
deoxygenated, causing the smooth muscle in the vessels of the blood to relax and elevating the
flow of blood to oxygen-depleted tissues. The erythrocytes can likewise advance vasodilatation
by discharging ATP under states of shear pressure and initiate an insusceptible reaction when
they are lysed by pathogens
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The erythrocytes also carry carbon dioxide which is a waste product in the process of
metabolism to the lungs where it is then excreted from the body. In many invertebrates, the
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. Erythropoiesis: Formation of Red Blood Cells. (2016, December 17). Retrieved from http://www.interactive-
biology.com/3969/erythropoiesis-formation-of-red-blood-cells/
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. Overmann J. Red Blood Cells. Interpretation of Equine Laboratory Diagnostics. 2017 Oct 5:113.
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pigment for carrying the oxygen is carried in the plasma the mammalian erythrocyte is
additionally adjusted without a corethe measure of oxygen required by the cell for its digestion
is consequently low, and most oxygen conveyed can be liberated into the tissues. The biconcave
state of the cell permits oxygen trade at a steady rate over the most significant conceivable
territory
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The erythrocytes develop in the bone marrow in different stages which starts from
hemocytoblast, which is a multi-potential cell in the mesenchyme which becomes norm oblast
(erythroblast) amid a development period of two to five days. The erythroblast is then gradually
filled with hemoglobin and its nucleus and particles in the cytoplasm, also known as
mitochondria, provide the cells its energy. In a late stage the reticulocyte cell turns into a wholly
developed red cell. The standard red cell in people lives 100 120 days. There are somewhere in
the range of 5.2 million red cells for every cubic millimeter of blood in the adult human
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Human bone marrow
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. Singh AK, Singh S, Garg G, Rizvi SI. Rapamycin mitigates erythrocyte membrane transport functions and oxidative
stress during aging in rats. Archives of physiology and biochemistry. 2018 Jan 1;124(1):45-53.
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. Pretorius E, Oore-ofe O, Mbotwe S, Bester J. Erythrocytes and their role as health indicator: Using structure in a
patient-orientated precision medicine approach. Blood reviews. 2016 Jul 1;30(4):263-74.