Pressure and Boyles Law

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Pressure and Boyle’s Law
According to Williams (182), intrapulmonary pressure is the pressure inside lungs. The
pressure usually varies between periods of inspiration and expiration. Atmospheric pressure
according to Theodore (182) is the pressure of gases within the environment. Both
intrapulmonary pressure and atmospheric pressure are measured using millimeters of mercury as
the unit of measurement (mm Hg). At sea level, the atmospheric pressure is approximately 760
mm Hg while the intrapulmonary pressure is usually slightly higher at around 762 mm Hg
(Theodore 182-183). The processes of inspiration and expiration are both active processes in
which the internal intercostal and contracting diaphragm work to increase the dimensions, and
conversely the area of the thorax. According to Boyle’s Law, the volume occupied by a gas in a
container has an inverse relationship to the pressure of the said gas. As such, an increment of the
volume of a gas is responsible for decreasing the pressure of a gas. The reverse is also true. The
changes in the intrapulmonary and atmospheric pressure are responsible for the breathing
process.
When relating the intrapulmonary pressure, the atmospheric pressure and airflow to
Boyle’s Law, it can be argued that an increase in the volume of the lungs results to a slight
decrease in the intrapulmonary pressure below the atmospheric pressure which causes air to flow
inside the lungs down the pressure gradient (Theodore 32). Conversely, when the muscles
responsible for inspiration relax, then there is a resultant decrease in the volume of the thoracic
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cavity which causes the intrapulmonary pressure to slightly rise above the atmospheric pressure.
As such, air is pushed out of the lungs (down its pressure gradient). The resistance in the airways
is usually very minimal. The assumption taken in the argument is that the lungs act as the
container holding the gas. Only a small pressure gradient between the aforementioned pressures
is needed for inspiration and expiration to occur.
Asthma is a long-term disease affecting the lungs which results in the narrowing and
inflammation of an individual’s airways (Douglas and Elward 9-10). For one to understand
asthma, it is important that they first comprehend how the airways and lungs of a human work.
Individuals with asthma have their airways inflamed. As a result, their airways are sensitive and
swollen (Douglas and Elward 10). These airways often react strongly to some substances if
inhaled. During such reactions, the muscles around the airways tighten and thus narrow the
airways limiting the air flowing into the lungs.
The pressure gradient is responsible for airflow. When there is an increase in the airway
resistance in asthma patients, there is a decrease in the amount of air flowing into the lungs. As
such, the volume of the lungs is much smaller than the required causing an increase in the
intrapulmonary pressure within the lungs. This affects the pressure gradient and makes inhalation
and expiration hard for an individual with asthma. The effect is that an individual will make
whizzing sounds as they struggle to breath, encounter shortness of breath, have their chest
tightening and cough repeatedly.
In conclusion, the changes in the atmospheric pressure and intrapulmonary pressure are
responsible for the breathing process. These changes in pressure concur with Boyles Law of the
relationship between the volume and pressure of a gas. For asthma patients, the breathing process
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is usually affected by the constricted airways which affect both the pressure and volume of
oxygen taken in and out of the lungs during the breathing process.
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Works Cited
Douglas, Graham and Kurtis Elward. Asthma: Clinician's Desk Reference. Florida: CRC Press,
2010. Print.
Theodore, Marcy. Medical Management of Pulmonary Diseases: Clinical Guides to Medical
Management. Florida: CRC Press, 1999. Print.
Williams , Lippincott. Anatomy and Physiology Made Incredibly Easy! New York: Lippincott
Williams & Wilkins,, 2009. Print.

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