Science

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Science
Question 1: Bone Formation and Remodeling
Bone formation begins when the fetus starts developing and it continues through childhood and
adolescent stages. Bone remodeling is a lifelong process that consists of resorption and
ossification, that is, the breakdown of old bones and formation of new ones (Goodenough and
McGuire 175). Bone remodeling is fundamental in shaping the skeleton and repairing bone
fractures in the human body. The formation and remodeling of bones occur due to the presence
of cells such as osteoblasts, osteocytes, and osteoclasts in the bone marrow. Osteoblasts produce
alkaline phosphatase that creates sites for deposition of calcium and phosphate ions, which allow
bone mineral to grow (Goodenough and McGuire 176). The bone-forming cells that lie below
the surface of bone synthesize osteoid, which is later mineralized to form a bone. During the
resorption of bones, osteoclasts move to particular sites on the external part of the bone and
release phosphatase acid, which detaches the calcium ions from the bone hence breaking it down.
To help speed up the rate of bone formation, people should take plenty of foods rich in
calcium such as turnips and kales. About 99% of calcium is absorbed in the bones to maintain its
density and quality (Goodenough and McGuire 176). Foods rich in vitamin D such as salmon
and tuna should also be taken in plenty to improve the ability of the body to absorb calcium,
which is a key factor in bone formation.
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Question 2: Parathyroid Gland
Each of the four parathyroid glands in the human body is located in the neck behind the thyroid
(Goodenough and McGuire 267). A parathyroid gland controls the level of calcium in the body
by secreting a parathyroid hormone (PTH). The gland works like a thermostat to keep the levels
of calcium within a constant range. When the level of calcium ions in the blood is too low, the
parathyroid gland releases PTH to raise the calcium level up to normal. PTH raises the level of
calcium in the blood by breaking down a bone where most of the ions are stored. The hormone
also increases the capability of the kidney to keep more calcium that would be lost with urine
(Goodenough and McGuire 268). When the level of calcium is normal or high, parathyroid gland
stops releasing PTH.
Question 3: Decubitus Ulcer
Decubitus ulcers are damages to the skin or underlying tissue that occur over the bony area due
to pressure or friction. The most common sites for decubitus ulcers are hips, back, ankles and
buttocks (Macon and Solan). The disorder develops in stages, which helps the health
practitioners to diagnose and treat it. At the first stage, the skin is not broken, but it is discolored.
The area where decubitus ulcers have attacked may appear red if the skin has a light complexion.
The discoloration may be blue or purple if the skin has a dark complexion. At the second stage,
the skin is open and show signs of dead tissues around the wound (Macon and Solan). The ulcer
is shallow with a red or pink wound bed and might show some blisters filled with fluid. When
the ulcer reaches stage three, it deepens within the skin. It affects the subcutaneous layer and
may form a crater on the skin. The skin might also produce pus from the colored sores. The final
stage of development of decubitus ulcer is stage four where many layers of the skin are affected
including the muscles and bones. The sores might contain a dark substance known as eschar.
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The decubitus ulcer is a serious condition because it is very difficult to treat if it is not
detected at the early stages. The condition develops through simple lifestyle activities like
avoiding frequent turning when one is asleep. The ulcer can lead to complications such as
cellulitis that result from a bacterial infection in the deepest skin layer (Macon and Solan).
Cellulitis can later result in a life-threatening complication known as septicemia, which kills
people on frequent occasions.
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Works Cited
Goodenough, J., and B. McGuire. Biology of Humans: Concepts, applications, and issues.
Benjamin Cummings, 2014.
Macon, Lee, and Mathew Solan. “What You Should Know About Decubitus Ulcers.” Healthline.
3 Nov. 2015, http://www.healthline.com/health/pressure-ulcer#Overview1. Accessed 16
Feb. 2017.

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